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Shimon Sakaguchi
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== Frequently Asked Questions (FAQ) == '''Q1. Who is Dr. Shimon Sakaguchi?''' A Japanese immunologist and Nobel Laureate known for discovering '''regulatory T cells''', which prevent autoimmune diseases. '''Q2. What did he win the Nobel Prize for?''' For discovering and defining the function of regulatory T cells (T-regs) and their role in maintaining immune tolerance. '''Q3. Why is his work important?''' It explains how the immune system avoids attacking the body’s own tissues and provides the foundation for therapies that treat autoimmune diseases and cancer. '''Q4. When did he make the discovery?''' He first identified T-regs in the 1990s; their molecular mechanism (via FOXP3) was later uncovered in collaboration with Brunkow and Ramsdell in 2001. '''Q5. What is he doing now?''' He continues to lead immunology research at Osaka University’s IFReC, advancing T-reg-based therapies. ----
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